Rome to Desio Trains

Rome to Desio trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Rome and Desio takes 5h 13m and the fastest train takes 4h 6m. The train service runs several times per day from Rome to Desio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 13m
Duration: 582 km
Distance: €100
Average price: Every 2 hours
Frequency

Train via Milan Rogoredo (Trenitalia)

best

Take the train from Roma Termini to Milano Rogoredotrain Fr

4h 37m

€85–165

Rome to Desio train times

Trains run every 2 hours between Rome and Desio. The earliest departure is at 4:55 AM at night, and the last departure from Rome is at 7:50 PM which arrives into Desio at 7:21 AM. All services require a transfer, and take on average 5h 13m. The schedules shown below are for the next available departures.

Departing Tuesday, September 1, 2026

8:05 AM → 12:51 PM
4h 46m • 1 change
9:10 AM → 1:51 PM
4h 41m • 1 change
10:10 AM → 2:51 PM
4h 41m • 1 change
11:00 AM → 3:51 PM
4h 51m • 1 change
Show more

Departing Wednesday, September 2, 2026

4:55 AM → 9:51 AM
4h 56m • 1 change
5:40 AM → 10:51 AM
5h 11m • 1 change
7:10 AM → 11:51 AM
4h 41m • 1 change
8:05 AM → 12:51 PM
4h 46m • 1 change
Show more

Departing Thursday, September 3, 2026

4:55 AM → 9:51 AM
4h 56m • 1 change
5:40 AM → 10:51 AM
5h 11m • 1 change
7:10 AM → 11:51 AM
4h 41m • 1 change
8:05 AM → 12:51 PM
4h 46m • 1 change
Show more

Departing Friday, September 4, 2026

5:40 AM → 10:51 AM
5h 11m • 1 change
7:10 AM → 11:51 AM
4h 41m • 1 change
8:05 AM → 12:51 PM
4h 46m • 1 change
9:10 AM → 1:51 PM
4h 41m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Rome to Desio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.