The average train between Rome and Eisenach takes 18h 1m and the fastest train takes 13h 38m. The train service runs several times per day from Rome to Eisenach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Rome and Eisenach. The earliest departure is at 7:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Eisenach at 5:08 PM. All services require a transfer at Milano Centrale and take an average of 18h 1m. The schedules shown below are for the next available departures.



13h 38m • 3 changes
Arrives next day



18h 58m • 3 changes
Arrives next day



21h 3m • 3 changes



13h 38m • 3 changes
Arrives next day



18h 58m • 3 changes
Arrives next day



21h 3m • 3 changes
Arrives next day



20h 58m • 3 changes
Arrives next day



21h 3m • 3 changes
Want to know about travelling from Rome to Eisenach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Eisenach. However, there are services departing from Rome station and arriving at Eisenach station via Milano Centrale. The journey, including transfers, takes approximately 18h 1m.
Rome to Eisenach train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Eisenach train services, operated by ItaloTreno, arrive at Eisenach Hbf station.
Book your Rome to Eisenach train tickets online with ItaloTreno, Trenitalia EuroCity and 2 other operators.
The distance between Rome and Eisenach is 1,023.3 km. The road distance is 1,473 km.
You can take a train from Roma Termini to Eisenach Hbf via Milano Centrale, Basel SBB, and Frankfurt in around 14h 45m.