Rome to Karlsruhe Trains

Rome to Karlsruhe trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Rome and Karlsruhe takes 11h 52m and the fastest train takes 10h 27m. The train service runs several times per day from Rome to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 52m
Duration: 1,136 km
Distance: €227
Average price: 3 times a day
Frequency

Train via Basel

best

Take the train from Roma Termini to Milano Centraletrain
Take the train from Milano Centrale to Basel Sbbtrain Ec
Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain 12 / ...

10h 37m

€180–315

Rome to Karlsruhe train times

Trains run 3 times a day between Rome and Karlsruhe. The earliest departure is at 6:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Karlsruhe at 1:57 PM. All services require a transfer at Milano Centrale and take an average of 11h 52m. The schedules shown below are for the next available departures.

Departing Wednesday, October 14, 2026

6:30 AM → 4:57 PM
10h 27m • 2 changes
7:30 AM → 5:57 PM
10h 27m • 2 changes
11:05 AM → 9:56 PM
10h 51m • 2 changes
2:05 PM → 6:57 AM
Arrives next day
16h 52m • 2 changes
Show more

Departing Thursday, October 15, 2026

6:30 AM → 4:57 PM
10h 27m • 2 changes
7:30 AM → 5:57 PM
10h 27m • 2 changes
11:05 AM → 9:56 PM
10h 51m • 2 changes
2:05 PM → 1:20 AM
Arrives next day
11h 15m • 2 changes

Departing Friday, October 16, 2026

6:30 AM → 4:57 PM
10h 27m • 2 changes
7:30 AM → 5:57 PM
10h 27m • 2 changes

Departing Saturday, October 17, 2026

7:30 AM → 5:57 PM
10h 27m • 2 changes

Departing Sunday, October 18, 2026

7:30 AM → 5:57 PM
10h 27m • 2 changes
8:05 PM → 1:57 PM
Arrives next day
17h 52m • 2 changes

Departing Monday, October 19, 2026

6:30 AM → 4:57 PM
10h 27m • 2 changes
7:30 AM → 5:57 PM
10h 27m • 2 changes
11:05 AM → 9:56 PM
10h 51m • 2 changes
2:05 PM → 1:20 AM
Arrives next day
11h 15m • 2 changes
Show more

Departing Tuesday, October 20, 2026

6:30 AM → 4:57 PM
10h 27m • 2 changes
7:30 AM → 5:57 PM
10h 27m • 2 changes
11:05 AM → 9:56 PM
10h 51m • 2 changes
2:05 PM → 1:20 AM
Arrives next day
11h 15m • 2 changes

Frequently asked questions

Want to know about travelling from Rome to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.