The average train between Rome and Karlsruhe Hauptbahnhof takes 12h 32m and the fastest train takes 9h 59m. The train service runs several times per day from Rome to Karlsruhe Hauptbahnhof. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Rome and Karlsruhe Hauptbahnhof. The earliest departure is at 6:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Karlsruhe Hauptbahnhof at 1:57 PM. All services require a transfer at Milano Centrale and take an average of 12h 32m. The schedules shown below are for the next available departures.


10h 27m • 2 changes

9h 59m • 2 changes

10h 51m • 2 changesArrives next day


16h 23m • 2 changes

10h 27m • 2 changes

9h 59m • 2 changes

10h 51m • 2 changesArrives next day


16h 23m • 2 changes

10h 27m • 2 changes

9h 59m • 2 changes

10h 51m • 2 changesArrives next day


11h 10m • 2 changes

10h 27m • 2 changes

9h 59m • 2 changes

10h 51m • 2 changesArrives next day


16h 23m • 2 changes

10h 27m • 2 changes

9h 59m • 2 changes

10h 51m • 2 changesArrives next day


16h 23m • 2 changesWant to know about travelling from Rome to Karlsruhe Hauptbahnhof? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Karlsruhe Hauptbahnhof. However, there are services departing from Roma Termini station and arriving at Karlsruhe Hauptbahnhof station via Milano Centrale station and Basel Sbb station. The journey, including transfers, takes approximately 12h 32m.
Rome to Karlsruhe Hauptbahnhof train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Karlsruhe Hauptbahnhof train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Karlsruhe Hauptbahnhof station.
Book your Rome to Karlsruhe Hauptbahnhof train tickets online with Omio.
The distance between Rome and Karlsruhe Hauptbahnhof is 850.7 km. The road distance is 1096 km.
You can take a train from Roma Termini to Karlsruhe Hauptbahnhof via Milano Centrale and Basel SBB in around 10h 29m.