The average train between Rome and L'Isle-sur-la-Sorgue takes 19h 14m and the fastest train takes 17h 48m. The train service runs several times per day from Rome to L'Isle-sur-la-Sorgue. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Rome and L'Isle-sur-la-Sorgue. The earliest departure is at 12:10 PM in the afternoon, and the last departure from Rome is at 8:05 PM which arrives into L'Isle-sur-la-Sorgue at 3:20 PM. All services require a transfer at Milano Centrale and take an average of 19h 14m. The schedules shown below are for the next available departures.
Arrives next day




18h 47m • 4 changes
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21h 15m • 4 changes
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17h 48m • 4 changes
Arrives next day




20h 15m • 4 changes
Arrives next day




17h 48m • 4 changes
Arrives next day




21h 15m • 4 changes
Arrives next day




17h 48m • 4 changes
Arrives next day




21h 15m • 4 changes
Want to know about travelling from Rome to L'Isle-sur-la-Sorgue? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to L'Isle-sur-la-Sorgue. However, there are services departing from Rome station and arriving at L'Isle-sur-la-Sorgue station via Milano Centrale. The journey, including transfers, takes approximately 19h 14m.
Rome to L'Isle-sur-la-Sorgue train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to L'Isle-sur-la-Sorgue train services, operated by ItaloTreno, arrive at Avignon Tgv station.
Book your Rome to L'Isle-sur-la-Sorgue train tickets online with ItaloTreno, Trenitalia and 3 other operators.
The distance between Rome and L'Isle-sur-la-Sorgue is 646.6 km. The road distance is 1,279 km.
You can take a train from Roma Termini to L'isle-Sur-La-Sorgue - Fontaine-De-Vaucluse via Milano Centrale, Lyon Part Dieu, Avignon Tgv, and Avignon Centre in around 11h 20m.