The average train between Rome and Leverkusen takes 17h 34m and the fastest train takes 13h 14m. The train service runs several times per day from Rome to Leverkusen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Rome and Leverkusen. The earliest departure is at 7:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Leverkusen at 4:44 PM. All services require a transfer at Milano Centrale and take an average of 17h 34m. The schedules shown below are for the next available departures.




13h 14m • 4 changes
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18h 34m • 4 changes
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20h 39m • 4 changes




13h 14m • 4 changes
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18h 34m • 4 changes
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20h 39m • 4 changes




13h 14m • 4 changes
Arrives next day




18h 34m • 4 changes
Arrives next day




20h 39m • 4 changes




13h 14m • 4 changes
Arrives next day




18h 34m • 4 changes
Arrives next day




20h 39m • 4 changes




13h 14m • 4 changes
Arrives next day




20h 34m • 4 changes
Arrives next day




20h 39m • 4 changes
Want to know about travelling from Rome to Leverkusen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Leverkusen. However, there are services departing from Rome station and arriving at Leverkusen station via Milano Centrale. The journey, including transfers, takes approximately 17h 34m.
Rome to Leverkusen train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Leverkusen train services, operated by ItaloTreno, arrive at Köln Messe/Deutz Bf station.
Book your Rome to Leverkusen train tickets online with ItaloTreno, Trenitalia EuroCity and 2 other operators.
The distance between Rome and Leverkusen is 1,098.7 km. The road distance is 1,447 km.
You can take a train from Roma Termini to Leverkusen Mitte via Milano Centrale, Basel SBB, Mannheim, Hauptbahnhof, Köln Messe/Deutz Bf, and Koeln Messe/Deutz in around 13h 10m.