The average train between Rome and Luxembourg takes 16h 23m and the fastest train takes 12h 44m. The train service runs several times per day from Rome to Luxembourg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Rome and Luxembourg. The earliest departure is at 7:30 AM in the morning, and the last departure from Rome is at 4:10 PM which arrives into Luxembourg at 2:15 PM. All services require a transfer at Milano Centrale and take an average of 16h 23m. The schedules shown below are for the next available departures.




14h 54m • 4 changes




12h 44m • 4 changes
Arrives next day




22h 5m • 4 changes




14h 54m • 4 changes




12h 44m • 4 changes
Arrives next day




22h 5m • 4 changes




14h 54m • 4 changes




12h 44m • 4 changes
Arrives next day




22h 5m • 4 changes
Want to know about travelling from Rome to Luxembourg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Luxembourg. However, there are services departing from Rome station and arriving at Luxembourg station via Milano Centrale. The journey, including transfers, takes approximately 16h 23m.
Rome to Luxembourg train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Luxembourg train services, operated by ItaloTreno, arrive at Luxembourg station.
Book your Rome to Luxembourg train tickets online with ItaloTreno, Trenitalia EuroCity and 3 other operators.
The distance between Rome and Luxembourg is 988.8 km. The road distance is 1,266 km.
You can take a train from Roma Termini to Luxembourg via Milano Centrale, Zuerich Hb, Zürich HB, Mulhouse, Mulhouse Ville, and Metz Ville in around 13h 19m.