Rome2Rio

Rome to Mainz trains

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Trip Overview

The average train between Rome and Mainz takes 14h 5m and the fastest train takes 11h 48m. The train service runs several times per day from Rome to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 5m
Duration
1,266 km
Distance
€272
Average price
4 times a day
Frequency

Train via Basel

best
  1. Take the train from Roma Termini to Milano Centraletrain train
  2. Take the train from Milano Centrale to Basel Sbbtrain train Ec
  3. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
  4. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
12h 36m
€201–405

Rome to Mainz train times

Trains run 4 times a day between Rome and Mainz. The earliest departure is at 6:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Mainz at 3:18 PM. All services require a transfer at Milano Centrale and take an average of 14h 5m. The schedules shown below are for the next available departures.

Departing Sunday, October 11, 2026

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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)18h 28m • 3 changes

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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)19h 13m • 3 changes

Departing Monday, October 12, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Süwex12h 13m • 3 changes

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)11h 48m • 3 changes

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)12h 48m • 3 changes

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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)15h 33m • 3 changes
  • Show more

Departing Tuesday, October 13, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Süwex12h 13m • 3 changes

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)11h 48m • 3 changes

  •  → 

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)12h 48m • 3 changes

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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)15h 33m • 3 changes
  • Show more

Departing Wednesday, October 14, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Süwex12h 13m • 3 changes

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)11h 48m • 3 changes

  •  → 

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)12h 48m • 3 changes

  •  → 

    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)18h 28m • 3 changes
  • Show more

Departing Thursday, October 15, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Süwex12h 13m • 3 changes

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)11h 48m • 3 changes

  •  → 

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)12h 48m • 3 changes

  •  → 

    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)15h 33m • 3 changes

Departing Friday, October 16, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Süwex12h 13m • 3 changes

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)11h 48m • 3 changes

Departing Saturday, October 17, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)11h 48m • 3 changes

Frequently asked questions

Want to know about travelling from Rome to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Mainz.ExpandLaunch map view
  • Distance: 1,266.1 km
  • Duration: 14h 5m

What companies run services between Rome, Italy and Mainz, Germany?

You can take a train from Roma Termini to Mainz, Hauptbahnhof via Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 12h 36m.

Operators