Rome2Rio

Rome to Manchester Piccadilly Station trains

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Trip Overview

The average train between Rome and Manchester Piccadilly Station takes 25h 41m and the fastest train takes 25h 9m. The train service runs several times per day from Rome to Manchester Piccadilly Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 41m
Duration
1,385 mi
Distance
£431
Average price
Twice daily
Frequency

Rome to Manchester Piccadilly Station train times

Trains run twice daily between Rome and Manchester Piccadilly Station. The earliest departure is at 12:10 PM in the afternoon, and the last departure from Rome is at 8:05 PM which arrives into Manchester Piccadilly Station at 9:19 PM. All services require a transfer at Milano Centrale and take an average of 25h 41m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast26h 14m • 4 changes

Departing Friday, November 13, 2026

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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast25h 9m • 4 changes
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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast25h 14m • 4 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast27h 9m • 4 changes
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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast25h 14m • 4 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast25h 9m • 4 changes
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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast26h 14m • 4 changes

Departing Monday, November 16, 2026

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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast25h 9m • 4 changes
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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast26h 14m • 4 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast25h 9m • 4 changes
  •  → 

    Arrives next day

    ItaloTrenoTrenitaliaTGV inOuiEurostarAvanti West Coast26h 14m • 4 changes

Frequently asked questions

Want to know about travelling from Rome to Manchester Piccadilly Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Manchester Piccadilly Station.ExpandLaunch map view
  • Distance: 1,385.4 mi
  • Duration: 25h 41m

What companies run services between Rome, Italy and Manchester Piccadilly Station, England?

You can take a train from Roma Termini to Manchester Piccadilly via Milano Centrale, Lyon Part Dieu, Lille Europe, London St Pancras Intl, and London Euston in around 17h 1m.

Operators