The average train between Rome and Melano takes 5h 18m and the fastest train takes 4h 44m. There is a train service every few hours from Rome to Melano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and Melano. The earliest departure is at 5:40 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Melano at 6:54 AM. All services require a transfer at Milano Centrale and take an average of 5h 18m. The schedules shown below are for the next available departures.


5h 14m • 2 changes


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4h 49m • 2 changes
Want to know about travelling from Rome to Melano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Melano. However, there are services departing from Rome station and arriving at Melano station via Milano Centrale. The journey, including transfers, takes approximately 5h 18m.
Rome to Melano train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Melano train services, operated by ItaloTreno, arrive at Mendrisio station.
The distance between Rome and Melano is 528.6 km. The road distance is 646 km.
You can take a train from Roma Termini to Maroggia-Melano via Milano Centrale and Mendrisio in around 4h 53m.