The average train between Rome and Melzo takes 4h 27m and the fastest train takes 3h 49m. There is a train service every few hours from Rome to Melzo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and Melzo. The earliest departure is at 5:40 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Melzo at 12:01 AM. All services require a transfer at Milano Rogoredo and take an average of 4h 27m. The schedules shown below are for the next available departures.

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4h 46m • 1 changeWant to know about travelling from Rome to Melzo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Melzo. However, there are services departing from Rome station and arriving at Melzo station via Milano Rogoredo. The journey, including transfers, takes approximately 4h 27m.
Rome to Melzo train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Melzo train services, operated by ItaloTreno, arrive at Melzo station.
Book your Rome to Melzo train tickets online with ItaloTreno and Trenord.
The distance between Rome and Melzo is 470.3 km. The road distance is 601 km.
You can take a train from Roma Termini to Melzo via Milano Rogoredo and Rho Fiera Milano in around 4h 2m.