The average train between Rome and Milan Cathedral takes 3h 48m and the fastest train takes 3h 23m. There is a train service every few hours from Rome to Milan Cathedral. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and Milan Cathedral. The earliest departure is at 5:40 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Milan Cathedral at 11:34 PM. All services require a transfer at Milano Rogoredo and take an average of 3h 48m. The schedules shown below are for the next available departures.

3h 58m • 1 change

3h 31m • 1 change

3h 57m • 1 change

3h 54m • 1 change

3h 58m • 1 change

3h 31m • 1 change

3h 57m • 1 change

3h 54m • 1 change

3h 58m • 1 change

3h 31m • 1 change

3h 57m • 1 change

3h 54m • 1 change

3h 58m • 1 change

3h 31m • 1 change

3h 57m • 1 change

3h 54m • 1 change
Want to know about travelling from Rome to Milan Cathedral? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Milan Cathedral. However, there are services departing from Rome station and arriving at Milan Cathedral station via Milano Rogoredo. The journey, including transfers, takes approximately 3h 48m.
Rome to Milan Cathedral train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Milan Cathedral train services, operated by ItaloTreno, arrive at Milano Rogoredo station.
The distance between Rome and Milan Cathedral is 477.2 km. The road distance is 582 km.
ItaloTreno operates a train from Roma Termini to Milano Rogoredo hourly. Tickets cost €70–150 and the journey takes 2h 54m.