The average train between Rome and Pisa (Station) takes 3h 47m and the fastest train takes 3h 1m. The train service runs several times per day from Rome to Pisa (Station). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Rome and Pisa (Station). The earliest departure is at 5:55 AM in the morning, and the last departure from Rome is at 9:40 PM which arrives into Pisa (Station) at 7:42 AM. All services require a transfer at Pisa Centrale and take an average of 3h 47m. The schedules shown below are for the next available departures.

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Want to know about travelling from Rome to Pisa (Station)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Pisa (Station). However, there are services departing from Rome station and arriving at Pisa (Station) station via Pisa Centrale. The journey, including transfers, takes approximately 3h 47m.
Rome to Pisa (Station) train services, operated by Trenitalia Frecce, depart from Roma Termini station.
Rome to Pisa (Station) train services, operated by Trenitalia Frecce, arrive at Pisa Centrale station.
Book your Rome to Pisa (Station) train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Rome and Pisa (Station) is 266.4 km. The road distance is 346 km.
Trenitalia Frecce operates a train from Roma Termini to Pisa Centrale hourly. Tickets cost €45–100 and the journey takes 2h 27m. Two other operators also service this route.