The average train between Rome and San Francesco Grande takes 3h 43m and the fastest train takes 3h 20m. There is a train service every few hours from Rome to San Francesco Grande. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and San Francesco Grande. The earliest departure is at 6:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into San Francesco Grande at 11:33 PM. All services require a transfer at Milano Centrale and take an average of 3h 43m. The schedules shown below are for the next available departures.

3h 40m • 1 change

3h 35m • 1 change

4h 5m • 1 change

3h 35m • 1 change

3h 40m • 1 change

3h 32m • 1 change

4h 5m • 1 change

3h 32m • 1 change

3h 40m • 1 change

3h 32m • 1 change

4h 5m • 1 change

3h 32m • 1 change
Want to know about travelling from Rome to San Francesco Grande? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to San Francesco Grande. However, there are services departing from Rome station and arriving at San Francesco Grande station via Milano Centrale. The journey, including transfers, takes approximately 3h 43m.
Rome to San Francesco Grande train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to San Francesco Grande train services, operated by ItaloTreno, arrive at Milano Centrale station.
The distance between Rome and San Francesco Grande is 477.8 km. The road distance is 587 km.
ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €70–150 and the journey takes 3h 5m.