The average train between Rome and Santa Domenica takes 7h 59m and the fastest train takes 5h 41m. The train service runs several times per day from Rome to Santa Domenica. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Rome and Santa Domenica. The earliest departure is at 8:56 AM in the morning, and the last departure from Rome is at 5:53 PM which arrives into Santa Domenica at 6:04 AM. All services require a transfer, and take on average 7h 59m. The schedules shown below are for the next available departures.

5h 43m • 1 change
7h 8m • 1 change
7h 22m • 1 change
6h 13m • 1 changeWant to know about travelling from Rome to Santa Domenica? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Santa Domenica. However, there are services departing from Roma Termini station and arriving at Santa Domenica station via Lamezia Terme C. station. The journey, including transfers, takes approximately 7h 59m.
Rome to Santa Domenica train services, operated by Trenitalia Frecce, depart from Roma Termini station.
Rome to Santa Domenica train services, operated by Trenitalia, arrive at Santa Domenica station.
Book your Rome to Santa Domenica train tickets online with Omio.
The distance between Rome and Santa Domenica is 459.3 km. The road distance is 627 km.
You can take a train from Roma Termini to Santa Domenica via Lamezia Terme C. in around 5h 53m.