The average train between Rome and Santa Maria Maggiore takes 10h 21m and the fastest train takes 6h 41m. The train service runs several times per day from Rome to Santa Maria Maggiore. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Rome and Santa Maria Maggiore. The earliest departure is at 7:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Santa Maria Maggiore at 10:11 AM. All services require a transfer at Milano Centrale and take an average of 10h 21m. The schedules shown below are for the next available departures.


7h 6m • 2 changes


6h 43m • 2 changes
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6h 43m • 2 changes
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6h 43m • 2 changes
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7h 1m • 2 changes
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6h 41m • 2 changes


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6h 43m • 2 changes


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6h 43m • 2 changes
Want to know about travelling from Rome to Santa Maria Maggiore? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Santa Maria Maggiore. However, there are services departing from Rome station and arriving at Santa Maria Maggiore station via Milano Centrale. The journey, including transfers, takes approximately 10h 21m.
Rome to Santa Maria Maggiore train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Santa Maria Maggiore train services, operated by ItaloTreno, arrive at Domodossola station.
The distance between Rome and Santa Maria Maggiore is 570.5 km. The road distance is 717 km.
You can take a train from Roma Termini to S Maria Maggiore via Milano Centrale and Domodossola in around 6h 32m.