The average train between Rome and Santhià takes 4h 54m and the fastest train takes 4h 9m. There is a train service every few hours from Rome to Santhià. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and Santhià. The earliest departure is at 5:40 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Santhià at 6:19 AM. All services require a transfer, and take on average 4h 54m. The schedules shown below are for the next available departures.

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4h 36m • 1 changeWant to know about travelling from Rome to Santhià? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Santhià. However, there are services departing from Rome station and arriving at Santhià station via Milano Rogoredo. The journey, including transfers, takes approximately 4h 54m.
Rome to Santhià train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Santhià train services, operated by ItaloTreno, arrive at Santhia station.
Book your Rome to Santhià train tickets online with ItaloTreno and Trenitalia.
The distance between Rome and Santhià is 519.2 km. The road distance is 651 km.
You can take a train from Roma Termini to Santhia via Rho-Fiera Milano in around 4h 1m.