The average train between Rome and Seregno takes 6h 9m and the fastest train takes 5h 32m. There is a train service every few hours from Rome to Seregno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and Seregno. The earliest departure is at 4:40 AM at night, and the last departure from Rome is at 7:40 PM which arrives into Seregno at 7:27 AM. All services require a transfer at Milan Rogoredo and take an average of 6h 9m. The schedules shown below are for the next available departures.


5h 47m • 2 changes


5h 52m • 2 changes


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5h 32m • 2 changes


5h 42m • 2 changes


5h 47m • 2 changes


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5h 42m • 2 changes


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5h 52m • 2 changes


5h 32m • 2 changes


5h 42m • 2 changes
Want to know about travelling from Rome to Seregno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Seregno. However, there are services departing from Rome station and arriving at Seregno station via Milano Rogoredo. The journey, including transfers, takes approximately 6h 9m.
Rome to Seregno train services, operated by Trenitalia Frecce, depart from Roma Termini station.
Rome to Seregno train services, operated by Trenitalia Frecce, arrive at Milano Rogoredo station.
Book your Rome to Seregno train tickets online with Trenitalia Frecce and Trenord.
The distance between Rome and Seregno is 493.6 km. The road distance is 585 km.
Trenitalia Frecce operates a train from Roma Termini to Milano Rogoredo every 30 minutes. Tickets cost €80–170 and the journey takes 3h 29m.