The average train between Rome and Vesoul takes 19h 44m and the fastest train takes 18h 38m. The train service runs several times per day from Rome to Vesoul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Rome and Vesoul. The earliest departure is at 11:05 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Vesoul at 2:43 PM. All services require a transfer at Milano Centrale and take an average of 19h 44m. The schedules shown below are for the next available departures.
Arrives next day



19h 17m • 3 changes
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19h 22m • 3 changes
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19h 17m • 3 changes
Arrives next day



19h 22m • 3 changes
Arrives next day



19h 17m • 3 changes
Arrives next day



19h 22m • 3 changes
Arrives next day



19h 17m • 3 changes
Arrives next day



19h 22m • 3 changes
Want to know about travelling from Rome to Vesoul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Vesoul. However, there are services departing from Rome station and arriving at Vesoul station via Milano Centrale. The journey, including transfers, takes approximately 19h 44m.
Rome to Vesoul train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Vesoul train services, operated by ItaloTreno, arrive at Vesoul station.
Book your Rome to Vesoul train tickets online with ItaloTreno, Trenitalia EuroCity and 2 other operators.
The distance between Rome and Vesoul is 810.1 km. The road distance is 1,086 km.
You can take a train from Roma Termini to Vesoul via Milano Centrale, Basel Sbb, Basel SBB, Mulhouse, and Mulhouse Ville in around 11h 57m.