The average train between Rome and Wiesbaden takes 16h 1m and the fastest train takes 12h 26m. The train service runs several times per day from Rome to Wiesbaden. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Rome and Wiesbaden. The earliest departure is at 7:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Wiesbaden at 4:26 PM. All services require a transfer at Milano Centrale and take an average of 16h 1m. The schedules shown below are for the next available departures.



12h 26m • 3 changes
Arrives next day



15h 46m • 3 changes
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19h 51m • 3 changes



12h 26m • 3 changes
Arrives next day



15h 46m • 3 changes
Arrives next day



19h 51m • 3 changes



12h 26m • 3 changes
Arrives next day



15h 46m • 3 changes
Arrives next day



19h 51m • 3 changes



12h 26m • 3 changes
Arrives next day



13h 21m • 3 changes
Arrives next day



20h 16m • 3 changes
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20h 21m • 3 changes
Want to know about travelling from Rome to Wiesbaden? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Wiesbaden. However, there are services departing from Rome station and arriving at Wiesbaden station via Milano Centrale. The journey, including transfers, takes approximately 16h 1m.
Rome to Wiesbaden train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Wiesbaden train services, operated by ItaloTreno, arrive at Wiesbaden Hbf station.
Book your Rome to Wiesbaden train tickets online with ItaloTreno, Trenitalia EuroCity and 3 other operators.
The distance between Rome and Wiesbaden is 966.8 km. The road distance is 1,315 km.
You can take a train from Roma Termini to Wiesbaden Hbf via Milano Centrale, Basel SBB, Frankfurt, and Frankfurt(Main)Hbf in around 12h 44m.