The average train between Sale and Southampton takes 5h 15m and the fastest train takes 4h 55m. There is a train service every few hours from Sale to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Sale and Southampton. The earliest departure is at 12:47 AM at night, and the last departure from Sale is at 11:47 PM which arrives into Southampton at 9:43 AM. All services require a transfer at Piccadilly and take an average of 5h 15m. The schedules shown below are for the next available departures.

4h 57m • 1 change

4h 56m • 1 change

4h 55m • 1 change

4h 58m • 1 change

4h 56m • 1 change

5h • 1 change

4h 56m • 1 change

4h 56m • 1 change

4h 56m • 1 change

5h • 1 change

4h 56m • 1 change

4h 56m • 1 change

4h 56m • 1 change

5h • 1 change

4h 56m • 1 change

4h 56m • 1 change

8h 56m • 1 change

4h 56m • 1 change

5h • 1 change

4h 56m • 1 change
Want to know about travelling from Sale to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sale to Southampton. However, there are services departing from Sale station and arriving at Southampton station via Southampton Central. The journey, including transfers, takes approximately 5h 15m.
Sale to Southampton train services, operated by Metrolink, depart from Manchester Piccadilly station.
Sale to Southampton train services, operated by Metrolink, arrive at Southampton Central station.
The distance between Sale and Southampton is 287.3 km. The road distance is 373 km.
Cross Country operates a train from Manchester Piccadilly to Southampton Central hourly. Tickets cost £120–180 and the journey takes 4h 18m.