The average train between Salzgitter and Frankfurt am Main takes 3h 25m and the fastest train takes 3h 18m. The train service runs several times per day from Salzgitter to Frankfurt am Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Salzgitter and Frankfurt am Main. The earliest departure is at 12:20 AM at night, and the last departure from Salzgitter is at 7:20 PM which arrives into Frankfurt am Main at 10:38 PM. All services require a transfer, and take on average 3h 25m. The schedules shown below are for the next available departures.

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3h 18m • 1 change

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9h 19m • 1 change

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3h 18m • 1 change
Want to know about travelling from Salzgitter to Frankfurt am Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Salzgitter to Frankfurt am Main. However, there are services departing from Salzgitter station and arriving at Frankfurt am Main station via Frankfurt (Main) Süd. The journey, including transfers, takes approximately 3h 25m.
Salzgitter to Frankfurt am Main train services, operated by Deutsche Bahn Regio (DB Regional), depart from Braunschweig, Hauptbahnhof station.
Salzgitter to Frankfurt am Main train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Frankfurt (Main) Süd station.
Book your Salzgitter to Frankfurt am Main train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Salzgitter and Frankfurt am Main is 257.1 km. The road distance is 370 km.
Deutsche Bahn Intercity (DB IC) operates a train from Braunschweig, Hauptbahnhof to Frankfurt (Main) Süd every 4 hours. Tickets cost €60–280 and the journey takes 2h 44m.