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San Antonio to St. Louis trains

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Trip Overview

The train between San Antonio and St. Louis takes 24h 42m. There is at least one train per day from San Antonio to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 42m
Duration
1,020 mi
Distance
$650
Average price
Once daily
Frequency

San Antonio to St. Louis train times

Trains run once daily between San Antonio and St. Louis. The earliest departure is at 6:48 AM in the morning, and the last departure from San Antonio is at 6:48 AM which arrives into St. Louis at 7:30 AM. All services run direct with no transfers required, and take on average 24h 42m. The schedules shown below are for the next available departures.

Departing Thursday, October 15, 2026

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    Arrives next day

    train train 24h 42m • Direct

Departing Friday, October 16, 2026

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    Arrives next day

    train train 24h 42m • Direct

Departing Saturday, October 17, 2026

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    Arrives next day

    train train 24h 42m • Direct

Departing Sunday, October 18, 2026

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    Arrives next day

    train train 24h 42m • Direct

Departing Monday, October 19, 2026

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    Arrives next day

    train train 24h 42m • Direct

Departing Tuesday, October 20, 2026

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    Arrives next day

    train train 24h 42m • Direct

Departing Wednesday, October 21, 2026

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    Arrives next day

    train train 24h 42m • Direct

Frequently asked questions

Want to know about travelling from San Antonio to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Antonio to St. Louis.ExpandLaunch map view
  • Distance: 1,019.7 mi
  • Duration: 24h 42m

What companies run services between San Antonio, TX, USA and St. Louis, MO, USA?

Amtrak operates a train from San Antonio Station to St. Louis once daily. Tickets cost $550–900 and the journey takes 24h 42m.

Operators