San Casciano to Rome Trains

Trip Overview

The average train between San Casciano and Rome takes 4h 11m and the fastest train takes 3h 21m. The train service runs several times per day from San Casciano to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 11m
Duration: 329 km
Distance: €50
Average price: Every 3 hours
Frequency

Train via Florence (Trenitalia)

best

Take the train from S.Frediano A Settimo to Firenze S.M.N.train Re
Take the train from Firenze S.M.N. to Roma Terminitrain Fr

3h 10m

€36–89

San Casciano to Rome train times

Trains run every 3 hours between San Casciano and Rome. The earliest departure is at 5:30 AM in the morning, and the last departure from San Casciano is at 10:41 PM which arrives into Rome at 8:20 AM. All services require a transfer, and take on average 4h 11m. The schedules shown below are for the next available departures.

Departing Saturday, August 15, 2026

4:12 PM → 7:55 PM
3h 43m • 1 change
6:12 PM → 9:43 PM
3h 31m • 1 change
10:41 PM → 9:05 AM
Arrives next day
10h 24m • 1 change

Departing Sunday, August 16, 2026

6:12 AM → 10:05 AM
3h 53m • 1 change
8:15 AM → 11:49 AM
3h 34m • 1 change
9:05 AM → 12:50 PM
3h 45m • 1 change
2:12 PM → 6:05 PM
3h 53m • 1 change
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Departing Monday, August 17, 2026

5:30 AM → 9:05 AM
3h 35m • 1 change
6:04 AM → 10:05 AM
4h 1m • 1 change
7:10 AM → 10:35 AM
3h 25m • 1 change
8:15 AM → 11:40 AM
3h 25m • 1 change
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Departing Tuesday, August 18, 2026

5:30 AM → 9:05 AM
3h 35m • 1 change
6:04 AM → 10:05 AM
4h 1m • 1 change
7:10 AM → 10:35 AM
3h 25m • 1 change
8:15 AM → 11:40 AM
3h 25m • 1 change
Show more

Departing Wednesday, August 19, 2026

5:30 AM → 9:05 AM
3h 35m • 1 change
6:04 AM → 10:05 AM
4h 1m • 1 change
7:10 AM → 10:35 AM
3h 25m • 1 change
8:15 AM → 11:40 AM
3h 25m • 1 change
Show more

Departing Thursday, August 20, 2026

5:30 AM → 9:05 AM
3h 35m • 1 change
6:04 AM → 10:05 AM
4h 1m • 1 change
7:10 AM → 10:35 AM
3h 25m • 1 change
8:15 AM → 11:40 AM
3h 25m • 1 change
Show more

Frequently asked questions

Want to know about travelling from San Casciano to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.