The average train between San Donato Milanese and Domodossola takes 3h 30m and the fastest train takes 2h 26m. The train service runs several times per day from San Donato Milanese to Domodossola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between San Donato Milanese and Domodossola. The earliest departure is at 6:47 AM in the morning, and the last departure from San Donato Milanese is at 11:17 PM which arrives into Domodossola at 8:43 AM. All services require a transfer at Milano Rogoredo and take an average of 3h 30m. The schedules shown below are for the next available departures.


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2h 26m • 2 changes


2h 56m • 2 changes


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2h 26m • 2 changes
Want to know about travelling from San Donato Milanese to Domodossola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from San Donato Milanese to Domodossola. However, there are services departing from San Donato Milanese station and arriving at Domodossola station via Domodossola. The journey, including transfers, takes approximately 3h 30m.
San Donato Milanese to Domodossola train services, operated by Trenord, depart from Milano Centrale station.
San Donato Milanese to Domodossola train services, operated by Trenord, arrive at Domodossola station.
Book your San Donato Milanese to Domodossola train tickets online with Trenord, Trenitalia Frecce and 2 other operators.
The distance between San Donato Milanese and Domodossola is 109 km. The road distance is 133 km.
Trenitalia EuroCity operates a train from Milano Centrale to Domodossola every 2 hours. Tickets cost €30–75 and the journey takes 1h 33m.