San Isidro to Madrid (Station) Trains

San Isidro to Madrid (Station) trains

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Trip Overview

The average train between San Isidro and Madrid (Station) takes 5h 51m and the fastest train takes 3h 33m. The train service runs several times per day from San Isidro to Madrid (Station). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 51m
Duration: 493 km
Distance: €91
Average price: 3 times a day
Frequency

Train (Renfe)

best

Take the train from Orihuela to Madrid Chamartíntrain Ave

4h 8m

€63–137

San Isidro to Madrid (Station) train times

Trains run 3 times a day between San Isidro and Madrid (Station). The earliest departure is at 9:52 AM in the morning, and the last departure from San Isidro is at 11:24 PM which arrives into Madrid (Station) at 9:32 AM. All services require a transfer at Orihuela and take an average of 5h 51m. The schedules shown below are for the next available departures.

Departing Sunday, August 23, 2026

10:02 AM → 2:29 PM
4h 27m • 3 changes
1:12 PM → 5:03 PM
3h 51m • 3 changes
11:12 PM → 9:33 AM
Arrives next day
10h 21m • 3 changes

Departing Monday, August 24, 2026

9:52 AM → 2:27 PM
4h 35m • 3 changes
1:12 PM → 4:57 PM
3h 45m • 3 changes
11:12 PM → 9:33 AM
Arrives next day
10h 21m • 3 changes

Departing Tuesday, August 25, 2026

9:52 AM → 2:27 PM
4h 35m • 3 changes
1:12 PM → 4:57 PM
3h 45m • 3 changes
11:12 PM → 9:33 AM
Arrives next day
10h 21m • 3 changes

Departing Wednesday, August 26, 2026

10:25 AM → 2:27 PM
4h 2m • 3 changes
1:24 PM → 4:57 PM
3h 33m • 3 changes
11:24 PM → 9:33 AM
Arrives next day
10h 9m • 3 changes

Departing Thursday, August 27, 2026

10:25 AM → 2:27 PM
4h 2m • 3 changes
1:24 PM → 4:57 PM
3h 33m • 3 changes
11:24 PM → 9:33 AM
Arrives next day
10h 9m • 3 changes

Departing Friday, August 28, 2026

10:25 AM → 2:34 PM
4h 9m • 3 changes
1:24 PM → 4:57 PM
3h 33m • 3 changes
11:24 PM → 9:32 AM
Arrives next day
10h 8m • 3 changes

Departing Saturday, August 29, 2026

10:25 AM → 2:29 PM
4h 4m • 3 changes
1:24 PM → 5:03 PM
3h 39m • 3 changes

Frequently asked questions

Want to know about travelling from San Isidro to Madrid (Station)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.