The average train between San Luis Obispo and San Ysidro takes 10h 41m and the fastest train takes 9h 48m. The train service runs several times per day from San Luis Obispo to San Ysidro. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between San Luis Obispo and San Ysidro. The earliest departure is at 6:11 AM in the morning, and the last departure from San Luis Obispo is at 4:17 PM which arrives into San Ysidro at 4:59 AM. All services require a transfer at San Diego and take an average of 10h 41m. The schedules shown below are for the next available departures.

9h 48m • 1 change

9h 54m • 1 change
Arrives next day

12h 49m • 1 change

9h 55m • 1 change

9h 54m • 1 change
Arrives next day

12h 49m • 1 change

9h 55m • 1 change

9h 54m • 1 change
Arrives next day

12h 42m • 1 change

9h 48m • 1 change

9h 54m • 1 change
Arrives next day

12h 42m • 1 change
Want to know about travelling from San Luis Obispo to San Ysidro? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from San Luis Obispo to San Ysidro. However, there are services departing from San Luis Obispo station and arriving at San Ysidro station via San Diego. The journey, including transfers, takes approximately 10h 41m.
San Luis Obispo to San Ysidro train services, operated by Amtrak, depart from San Luis Obispo station.
San Luis Obispo to San Ysidro train services, operated by Amtrak, arrive at San Diego station.
The distance between San Luis Obispo and San Ysidro is 451.1 km. The road distance is 584 km.
Amtrak operates a train from San Luis Obispo to San Diego 3 times a day. Tickets cost $110–230 and the journey takes 8h 55m.