The average train between Sant'Agnello and Siena takes 7h 25m and the fastest train takes 6h 11m. The train service runs several times per day from Sant'Agnello to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Sant'Agnello and Siena. The earliest departure is at 5:52 AM in the morning, and the last departure from Sant'Agnello is at 10:05 PM which arrives into Siena at 10:40 AM. All services require a transfer at Napoli P. Garibaldi and take an average of 7h 25m. The schedules shown below are for the next available departures.


6h 46m • 2 changes

6h 36m • 2 changes

6h 44m • 2 changes

6h 11m • 2 changes

6h 46m • 2 changes

6h 36m • 2 changes

6h 44m • 2 changes

6h 21m • 2 changes

6h 46m • 2 changes

6h 36m • 2 changes

6h 44m • 2 changes

6h 35m • 2 changes

6h 46m • 2 changes

6h 36m • 2 changes

6h 44m • 2 changes

6h 35m • 2 changes

6h 46m • 2 changes

6h 36m • 2 changes

6h 44m • 2 changes

6h 35m • 2 changesWant to know about travelling from Sant'Agnello to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sant'Agnello to Siena. However, there are services departing from Sant'Agnello station and arriving at Siena station via Napoli P. Garibaldi. The journey, including transfers, takes approximately 7h 25m.
Sant'Agnello to Siena train services, operated by Ente Autonomo Volturno S.r.l., depart from S. Agnello station.
Sant'Agnello to Siena train services, operated by Ente Autonomo Volturno S.r.l., arrive at Siena station.
Book your Sant'Agnello to Siena train tickets online with Ente Autonomo Volturno S.r.l., Trenitalia Frecce and Trenitalia.
The distance between Sant'Agnello and Siena is 391.9 km. The road distance is 609 km.
You can take a train from S. Agnello to Siena via Napoli P. Garibaldi, Napoli Centrale, and Firenze S.M.N. in around 6h 20m.