The average train between Sant'Agnello and Siena takes 6h 57m and the fastest train takes 6h 1m. There is a train service every few hours from Sant'Agnello to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Sant'Agnello and Siena. The earliest departure is at 5:36 AM in the morning, and the last departure from Sant'Agnello is at 10:06 PM which arrives into Siena at 10:40 AM. All services require a transfer at Napoli P.zza Garibaldi and take an average of 6h 57m. The schedules shown below are for the next available departures.


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6h 1m • 2 changesWant to know about travelling from Sant'Agnello to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sant'Agnello to Siena. However, there are services departing from Sant'Agnello station and arriving at Siena station via Napoli P.zza Garibaldi station and Firenze S.M.N. station. The journey, including transfers, takes approximately 6h 57m.
Sant'Agnello to Siena train services, operated by Campania Express, depart from Sant'Agnello station.
Sant'Agnello to Siena train services, operated by Trenitalia, arrive at Siena station.
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The distance between Sant'Agnello and Siena is 391.9 km. The road distance is 467 km.
You can take a train from Sant'Agnello to Siena via Napoli P.zza Garibaldi, Napoli Centrale, and Firenze S.M.N. in around 6h 47m.