The average train between Santa Domenica and Rome takes 7h and the fastest train takes 5h 20m. The train service runs several times per day from Santa Domenica to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Santa Domenica and Rome. The earliest departure is at 6:05 AM in the morning, and the last departure from Santa Domenica is at 8:39 PM which arrives into Rome at 11:25 AM. All services require a transfer, and take on average 7h. The schedules shown below are for the next available departures.

5h 20m • 1 change
7h 6m • 1 change
5h 53m • 1 change
6h 40m • 1 changeWant to know about travelling from Santa Domenica to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santa Domenica to Rome. However, there are services departing from Rosarno station and arriving at Roma Termini station via Roma Termini station. The journey, including transfers, takes approximately 7h.
Santa Domenica to Rome train services, operated by Trenitalia Frecce, depart from Rosarno station.
Santa Domenica to Rome train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
Book your Santa Domenica to Rome train tickets online with Omio.
The distance between Santa Domenica and Rome is 459.3 km. The road distance is 626 km.
Trenitalia Frecce operates a train from Rosarno to Roma Termini hourly. Tickets cost €80–140 and the journey takes 4h 36m. Two other operators also service this route.