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Santa Fe Depot to Irvine trains

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Trip Overview

The average train between Santa Fe Depot and Irvine takes 2h 55m and the fastest train takes 2h 19m. The train service runs several times per day from Santa Fe Depot to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 55m
Duration
88 mi
Distance
$61
Average price
Every 3 hours
Frequency

Santa Fe Depot to Irvine train times

Trains run every 3 hours between Santa Fe Depot and Irvine. The earliest departure is at 4:01 AM at night, and the last departure from Santa Fe Depot is at 9:01 PM which arrives into Irvine at 5:20 AM. All services require a transfer, and take on average 2h 55m. The schedules shown below are for the next available departures.

Departing Saturday, October 24, 2026

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    AmtrakMetrolink Trains2h 29m • 1 change
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    AmtrakMetrolink Trains2h 34m • 1 change
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    AmtrakMetrolink Trains2h 27m • 1 change
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    AmtrakMetrolink Trains2h 29m • 1 change

Departing Sunday, October 25, 2026

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    AmtrakMetrolink Trains2h 27m • 1 change
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    AmtrakMetrolink Trains2h 28m • 1 change
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    AmtrakMetrolink Trains2h 29m • 1 change
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    AmtrakMetrolink Trains2h 34m • 1 change
  • Show more

Departing Monday, October 26, 2026

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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
  • Show more

Departing Tuesday, October 27, 2026

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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
  • Show more

Departing Wednesday, October 28, 2026

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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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Departing Thursday, October 29, 2026

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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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Departing Friday, October 30, 2026

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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
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    AmtrakMetrolink Trains2h 19m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Santa Fe Depot to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santa Fe Depot to Irvine.ExpandLaunch map view
  • Distance: 87.9 mi
  • Duration: 2h 55m

What companies run services between Santa Fe Depot, San Diego County, CA, USA and Irvine, CA, USA?

Amtrak operates a train from San Diego to Irvine hourly. Tickets cost $45–70 and the journey takes 1h 50m.

Operators