The average train between Santa Margherita Ligure and Brussels takes 17h 10m and the fastest train takes 13h 12m. The train service runs several times per day from Santa Margherita Ligure to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Santa Margherita Ligure and Brussels. The earliest departure is at 8:20 AM in the morning, and the last departure from Santa Margherita Ligure is at 8:14 PM which arrives into Brussels at 3:48 PM. All services require a transfer at Genova P.Za Principe and take an average of 17h 10m. The schedules shown below are for the next available departures.





13h 12m • 5 changes
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17h 48m • 5 changes
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20h 46m • 5 changes





13h 12m • 5 changes
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18h 48m • 5 changes
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19h 20m • 5 changes





13h 14m • 5 changes
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21h 48m • 5 changes
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19h 39m • 5 changes





13h 14m • 5 changes
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18h 1m • 5 changes
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19h 53m • 5 changes
Want to know about travelling from Santa Margherita Ligure to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santa Margherita Ligure to Brussels. However, there are services departing from Santa Margherita Ligure station and arriving at Brussels station via Torino Lingotto. The journey, including transfers, takes approximately 17h 10m.
Santa Margherita Ligure to Brussels train services, operated by Trenitalia, depart from Genova P.Za Principe station.
Santa Margherita Ligure to Brussels train services, operated by Trenitalia, arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Santa Margherita Ligure to Brussels train tickets online with Trenitalia, TGV inOui and 3 other operators.
The distance between Santa Margherita Ligure and Brussels is 810.7 km. The road distance is 1,215 km.
You can take a train from S.Margherita L.-Port to Brussel-Zuid / Bruxelles-Midi via Genova P.Za Principe, Torino Lingotto, Torino Porta Susa, Paris Gare de Lyon, and Paris Nord in around 11h 23m.