The average train between Santa Margherita Ligure and Iseo takes 6h 58m and the fastest train takes 4h 42m. The train service runs several times per day from Santa Margherita Ligure to Iseo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Santa Margherita Ligure and Iseo. The earliest departure is at 6:07 AM in the morning, and the last departure from Santa Margherita Ligure is at 7:46 PM which arrives into Iseo at 8:24 AM. All services require a transfer at Milano Centrale and take an average of 6h 58m. The schedules shown below are for the next available departures.


5h 17m • 2 changes


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4h 42m • 2 changes
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12h 38m • 2 changes


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6h 22m • 2 changes


4h 42m • 2 changes
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12h 38m • 2 changes


5h 17m • 2 changes


5h 27m • 2 changes


4h 42m • 2 changes
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12h 38m • 2 changes


5h 17m • 2 changes


5h 27m • 2 changes


4h 42m • 2 changes
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12h 38m • 2 changes


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6h 22m • 2 changes


4h 42m • 2 changes
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12h 38m • 2 changes
Want to know about travelling from Santa Margherita Ligure to Iseo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santa Margherita Ligure to Iseo. However, there are services departing from Santa Margherita Ligure station and arriving at Iseo station via Milano Centrale. The journey, including transfers, takes approximately 6h 58m.
Santa Margherita Ligure to Iseo train services, operated by Trenitalia Intercity, depart from S.Margherita L.-Port station.
Santa Margherita Ligure to Iseo train services, operated by Trenitalia Intercity, arrive at Brescia station.
Book your Santa Margherita Ligure to Iseo train tickets online with Trenitalia Intercity, Trenitalia Frecce and Trenord.
The distance between Santa Margherita Ligure and Iseo is 161.5 km. The road distance is 273 km.
You can take a train from S.Margherita L.-Port to Iseo via Milano Centrale and Brescia in around 4h 23m.