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Santa Margherita to Rome trains

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Trip Overview

The average train between Santa Margherita and Rome takes 4h 49m and the fastest train takes 4h 2m. The train service runs several times per day from Santa Margherita to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 49m
Duration
601 km
Distance
€85
Average price
Every 3 hours
Frequency

Santa Margherita to Rome train times

Trains run every 3 hours between Santa Margherita and Rome. The earliest departure is at 6:23 AM in the morning, and the last departure from Santa Margherita is at 7:23 PM which arrives into Rome at 9:19 AM. All services require a transfer at Milano Greco Pirelli and take an average of 4h 49m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Departing Friday, November 13, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Departing Monday, November 16, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Departing Tuesday, November 17, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Departing Wednesday, November 18, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Frequently asked questions

Want to know about travelling from Santa Margherita to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santa Margherita to Rome.ExpandLaunch map view
  • Distance: 600.9 km
  • Duration: 4h 49m

What companies run services between Santa Margherita, Lombardy, Italy and Rome, Italy?

ItaloTreno operates a train from Milano Centrale to Roma Termini every 30 minutes. Tickets cost €65–110 and the journey takes 3h 5m.

Operators