Santa Margherita to Rome Trains

Santa Margherita to Rome trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Santa Margherita and Rome takes 5h 1m and the fastest train takes 4h 24m. There is a train service every few hours from Santa Margherita to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 1m
Duration: 605 km
Distance: €90
Average price: Hourly
Frequency

Train

best

Take the train from Milano Centrale to Roma Terminitrain 9995 / ...

4h 22m

€74–123

Santa Margherita to Rome train times

Trains run hourly between Santa Margherita and Rome. The earliest departure is at 12:06 AM at night, and the last departure from Santa Margherita is at 6:36 PM which arrives into Rome at 11:24 PM. All services require a transfer at Seregno and take an average of 5h 1m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

6:36 AM → 11:00 AM
4h 24m • 2 changes
7:36 AM → 12:19 PM
4h 43m • 2 changes
8:36 AM → 1:24 PM
4h 48m • 2 changes
9:36 AM → 2:30 PM
4h 54m • 2 changes
Show more

Departing Wednesday, November 11, 2026

12:06 AM → 9:19 AM
9h 13m • 2 changes
6:36 AM → 11:00 AM
4h 24m • 2 changes
7:36 AM → 12:19 PM
4h 43m • 2 changes
8:36 AM → 1:24 PM
4h 48m • 2 changes
Show more

Departing Thursday, November 12, 2026

12:06 AM → 9:19 AM
9h 13m • 2 changes
6:36 AM → 11:00 AM
4h 24m • 2 changes
7:36 AM → 12:19 PM
4h 43m • 2 changes
8:36 AM → 1:24 PM
4h 48m • 2 changes
Show more

Departing Friday, November 13, 2026

12:06 AM → 9:19 AM
9h 13m • 2 changes
6:36 AM → 11:00 AM
4h 24m • 2 changes
7:36 AM → 12:19 PM
4h 43m • 2 changes
8:36 AM → 1:24 PM
4h 48m • 2 changes
Show more

Departing Saturday, November 14, 2026

12:06 AM → 9:19 AM
9h 13m • 2 changes
6:36 AM → 11:00 AM
4h 24m • 2 changes
7:36 AM → 12:19 PM
4h 43m • 2 changes
8:36 AM → 1:24 PM
4h 48m • 2 changes
Show more

Departing Sunday, November 15, 2026

12:06 AM → 9:19 AM
9h 13m • 2 changes
6:36 AM → 11:00 AM
4h 24m • 2 changes
7:36 AM → 12:19 PM
4h 43m • 2 changes
8:36 AM → 1:24 PM
4h 48m • 2 changes
Show more

Departing Monday, November 16, 2026

12:06 AM → 9:19 AM
9h 13m • 2 changes
6:36 AM → 11:00 AM
4h 24m • 2 changes
7:36 AM → 12:19 PM
4h 43m • 2 changes
8:36 AM → 1:24 PM
4h 48m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Santa Margherita to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.