The average train between Santa Maria Novella and Interlaken takes 7h 38m and the fastest train takes 5h 26m. The train service runs several times per day from Santa Maria Novella to Interlaken. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Santa Maria Novella and Interlaken. The earliest departure is at 7:55 AM in the morning, and the last departure from Santa Maria Novella is at 9:55 PM which arrives into Interlaken at 10:21 AM. All services require a transfer at Firenze S.M.N. and take an average of 7h 38m. The schedules shown below are for the next available departures.


6h 26m • 2 changes


6h 30m • 2 changes
Arrives next day


12h 26m • 2 changes


5h 26m • 2 changes


5h 30m • 2 changes
Arrives next day


12h 26m • 2 changes


5h 26m • 2 changes


5h 30m • 2 changes
Arrives next day


12h 26m • 2 changes


5h 26m • 2 changes


5h 30m • 2 changes
Arrives next day


12h 26m • 2 changes
Want to know about travelling from Santa Maria Novella to Interlaken? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santa Maria Novella to Interlaken. However, there are services departing from Santa Maria Novella station and arriving at Interlaken station via Milano Centrale. The journey, including transfers, takes approximately 7h 38m.
Santa Maria Novella to Interlaken train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
Santa Maria Novella to Interlaken train services, operated by Trenitalia Frecce, arrive at Spiez station.
The distance between Santa Maria Novella and Interlaken is 418.6 km. The road distance is 542 km.
You can take a vehicle from Santa Maria Novella to Interlaken West via Firenze S.M.N., Milano Centrale, and Spiez in around 6h 20m.