The average train between Santa Maria Novella and Piazza del Duomo takes 2h 22m and the fastest train takes 2h 1m. There is a train service every few hours from Santa Maria Novella to Piazza del Duomo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Santa Maria Novella and Piazza del Duomo. The earliest departure is at 6:55 AM in the morning, and the last departure from Santa Maria Novella is at 9:55 PM which arrives into Piazza del Duomo at 5:55 AM. All services require a transfer at Firenze S.M.N. and take an average of 2h 22m. The schedules shown below are for the next available departures.

2h 56m • 1 change

2h 18m • 1 change

2h 14m • 1 change

2h 10m • 1 change

2h 7m • 1 change

2h 49m • 1 change

2h 19m • 1 change

2h 13m • 1 change

2h 9m • 1 change

2h 2m • 1 change

2h 51m • 1 change

2h 18m • 1 change
Want to know about travelling from Santa Maria Novella to Piazza del Duomo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santa Maria Novella to Piazza del Duomo. However, there are services departing from Santa Maria Novella station and arriving at Piazza del Duomo station via Milano Rogoredo. The journey, including transfers, takes approximately 2h 22m.
Santa Maria Novella to Piazza del Duomo train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
Santa Maria Novella to Piazza del Duomo train services, operated by Trenitalia Frecce, arrive at Milano Rogoredo station.
The distance between Santa Maria Novella and Piazza del Duomo is 248.7 km. The road distance is 302 km.
Trenitalia Frecce operates a train from Firenze S.M.N. to Milano Rogoredo every 30 minutes. Tickets cost €40–90 and the journey takes 1h 44m. Three other operators also service this route.