The average train between Santander and Grenoble takes 22h 16m and the fastest train takes 15h 40m. The train service runs several times per day from Santander to Grenoble. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Santander and Grenoble. The earliest departure is at 6:48 AM in the morning, and the last departure from Santander is at 7:00 PM which arrives into Grenoble at 10:28 PM. All services require a transfer at Madrid Chamartín and take an average of 22h 16m. The schedules shown below are for the next available departures.
Arrives next day




24h 30m • 4 changes
Arrives next day




26h 28m • 4 changes




15h 40m • 4 changes
Arrives next day




24h 30m • 4 changes
Arrives next day




26h 28m • 4 changes




15h 40m • 4 changes
Arrives next day




24h 30m • 4 changes
Arrives next day




26h 28m • 4 changes
Want to know about travelling from Santander to Grenoble? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santander to Grenoble. However, there are services departing from Santander station and arriving at Grenoble station via Madrid Chamartín. The journey, including transfers, takes approximately 22h 16m.
Santander to Grenoble train services, operated by Renfe Viajeros, depart from Santander station.
Santander to Grenoble train services, operated by Renfe Viajeros, arrive at Grenoble station.
Book your Santander to Grenoble train tickets online with Renfe Viajeros, Renfe Cercanias and 3 other operators.
The distance between Santander and Grenoble is 780.4 km. The road distance is 1,710 km.
You can take a train from Santander to Grenoble via Madrid Chamartín, Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, and Valence Tgv Rhone-Alpes Sud in around 14h 42m.