The average train between Santander and León takes 4h 10m and the fastest train takes 3h 11m. The train service runs several times per day from Santander to León. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Santander and León. The earliest departure is at 6:48 AM in the morning, and the last departure from Santander is at 7:00 PM which arrives into León at 10:30 PM. All services require a transfer, and take on average 4h 10m. The schedules shown below are for the next available departures.

4h 48m • 1 change

4h 21m • 1 change

4h 27m • 1 change

4h 31m • 1 change

4h 48m • 1 change

4h 21m • 1 change

4h 27m • 1 change

4h 31m • 1 change

4h 48m • 1 change

4h 21m • 1 change

4h 27m • 1 change

4h 44m • 1 change
Want to know about travelling from Santander to León? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santander to León. However, there are services departing from Santander station and arriving at León station via Palencia. The journey, including transfers, takes approximately 4h 10m.
Santander to León train services, operated by Renfe Viajeros, depart from Santander station.
Santander to León train services, operated by Renfe Viajeros, arrive at Leon station.
Book your Santander to León train tickets online with Renfe Viajeros and Renfe AVE.
The distance between Santander and León is 172.8 km. The road distance is 328 km.
You can take a train from Santander to Leon via Palencia in around 3h 16m.