The average train between Santander and Madrid Atocha Station takes 4h 40m and the fastest train takes 4h 23m. The train service runs several times per day from Santander to Madrid Atocha Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Santander and Madrid Atocha Station. The earliest departure is at 6:48 AM in the morning, and the last departure from Santander is at 7:00 PM which arrives into Madrid Atocha Station at 11:43 PM. All services require a transfer at Madrid Chamartín and take an average of 4h 40m. The schedules shown below are for the next available departures.

4h 58m • 1 change

4h 23m • 1 change

4h 33m • 1 change

4h 31m • 1 change

4h 58m • 1 change

4h 23m • 1 change

4h 33m • 1 change

4h 31m • 1 change

4h 58m • 1 change

4h 23m • 1 change

4h 28m • 1 change

4h 31m • 1 change

4h 58m • 1 change

4h 23m • 1 change

4h 28m • 1 change

4h 31m • 1 change

4h 57m • 1 change

4h 23m • 1 change

4h 27m • 1 change

4h 36m • 1 change

4h 58m • 1 change

4h 23m • 1 change

4h 28m • 1 change

4h 31m • 1 change
Want to know about travelling from Santander to Madrid Atocha Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santander to Madrid Atocha Station. However, there are services departing from Santander station and arriving at Madrid Atocha Station station via Madrid Chamartín. The journey, including transfers, takes approximately 4h 40m.
Santander to Madrid Atocha Station train services, operated by Renfe Viajeros, depart from Santander station.
Santander to Madrid Atocha Station train services, operated by Renfe Viajeros, arrive at Madrid Chamartín station.
Book your Santander to Madrid Atocha Station train tickets online with Renfe Viajeros and Renfe Cercanias.
The distance between Santander and Madrid Atocha Station is 340.5 km. The road distance is 449 km.
Renfe Viajeros operates a train from Santander to Madrid Chamartín every 4 hours. Tickets cost €55–85 and the journey takes 4h 14m.