Rome2Rio

Santander to Madrid City Center trains

Find Transport to Madrid City Center

View schedule

Trip Overview

The average train between Santander and Madrid City Center takes 4h 27m and the fastest train takes 4h 14m. The train service runs several times per day from Santander to Madrid City Center. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 27m
Duration
447 km
Distance
€66
Average price
3 times a day
Frequency

Santander to Madrid City Center train times

Trains run 3 times a day between Santander and Madrid City Center. The earliest departure is at 7:05 AM in the morning, and the last departure from Santander is at 7:00 PM which arrives into Madrid City Center at 11:38 PM. All services require a transfer, and take on average 4h 27m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 27m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 38m • 1 change

Departing Friday, October 23, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 27m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 38m • 1 change

Departing Saturday, October 24, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 35m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change

Departing Sunday, October 25, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 35m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 44m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 40m • 1 change

Departing Monday, October 26, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 27m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 38m • 1 change

Departing Tuesday, October 27, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 27m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 38m • 1 change

Departing Wednesday, October 28, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 27m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 38m • 1 change

Frequently asked questions

Want to know about travelling from Santander to Madrid City Center? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Madrid City Center.ExpandLaunch map view
  • Distance: 447.2 km
  • Duration: 4h 27m

What companies run services between Santander, Spain and Madrid City Center, Spain?

Renfe Viajeros operates a train from Santander to Madrid Chamartín every 4 hours. Tickets cost €55–80 and the journey takes 4h.

Operators