Rome2Rio

Santander to Madrid trains

Find Transport to Madrid

View schedule

Trip Overview

The average train between Santander and Madrid takes 4h 30m and the fastest train takes 4h 14m. There is at least one train per day from Santander to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 30m
Duration
447 km
Distance
€65
Average price
Once daily
Frequency

Santander to Madrid train times

Trains run once daily between Santander and Madrid. The earliest departure is at 7:05 AM in the morning, and the last departure from Santander is at 7:00 PM which arrives into Madrid at 11:40 PM. All services require a transfer, and take on average 4h 30m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 44m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 40m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 27m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 38m • 1 change

Frequently asked questions

Want to know about travelling from Santander to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Madrid.ExpandLaunch map view
  • Distance: 447.2 km
  • Duration: 4h 30m

What companies run services between Santander, Spain and Madrid, Spain?

Renfe Viajeros operates a train from Santander to Madrid Chamartín 5 times a day. Tickets cost €50–80 and the journey takes 4h.

Operators