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Santander to Madrid trains

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Trip Overview

The average train between Santander and Madrid takes 4h 26m and the fastest train takes 4h 14m. The train runs, on average, 3 times per week from Santander to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 26m
Duration
447 km
Distance
€65
Average price
3 times a week
Frequency

Santander to Madrid train times

Trains run 3 times a week between Santander and Madrid. The earliest departure is at 7:05 AM in the morning, and the last departure from Santander is at 7:00 PM which arrives into Madrid at 11:38 PM. All services require a transfer, and take on average 4h 26m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Renfe ViajerosRenfe Cercanias4h 27m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 14m • 1 change
  •  → 

    Renfe ViajerosRenfe Cercanias4h 38m • 1 change

Frequently asked questions

Want to know about travelling from Santander to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Madrid.ExpandLaunch map view
  • Distance: 447.2 km
  • Duration: 4h 26m

What companies run services between Santander, Spain and Madrid, Spain?

Renfe Viajeros operates a train from Santander to Madrid Chamartín 5 times a day. Tickets cost €50–80 and the journey takes 4h.

Operators