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Santander to Perugia trains

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Trip Overview

The train between Santander and Perugia takes 39h 25m. The train runs, on average, 5 times per week from Santander to Perugia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

39h 25m
Duration
2,628 km
Distance
€416
Average price
5 times a week
Frequency

Santander to Perugia train times

Trains run 5 times a week between Santander and Perugia. The service departs Santander at 7:05 AM in the morning, which arrives into Perugia at 22:30:00. All services require a transfer at Madrid Chamartín and take an average of 39h 25m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

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    Arrives next day

    Renfe ViajerosRenfe CercaniasRenfe ViajerosTGV inOuiTrenitaliaTrenitalia Frecce39h 25m • 5 changes

Departing Wednesday, November 4, 2026

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    Arrives next day

    Renfe ViajerosRenfe CercaniasRenfe ViajerosTGV inOuiTrenitaliaTrenitalia Frecce39h 25m • 5 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    Renfe ViajerosRenfe CercaniasRenfe ViajerosTGV inOuiTrenitaliaTrenitalia Frecce39h 25m • 5 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    Renfe ViajerosRenfe CercaniasRenfe ViajerosTGV inOuiTrenitaliaTrenitalia Frecce39h 25m • 5 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Renfe ViajerosRenfe CercaniasRenfe ViajerosTGV inOuiTrenitaliaTrenitalia Frecce39h 25m • 5 changes

Frequently asked questions

Want to know about travelling from Santander to Perugia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Perugia.ExpandLaunch map view
  • Distance: 2,628.3 km
  • Duration: 39h 25m

What companies run services between Santander, Spain and Perugia, Italy?

You can take a train from Santander to Perugia via Madrid Chamartín, Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Avignon Tgv, Lyon Part Dieu, and Torino Porta Susa in around 25h 41m.

Operators