The average train between Santander and San Isidro takes 10h 5m and the fastest train takes 8h 36m. The train service runs several times per day from Santander to San Isidro. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Santander and San Isidro. The earliest departure is at 6:48 AM in the morning, and the last departure from Santander is at 7:00 PM which arrives into San Isidro at 10:04 AM. All services require a transfer at Madrid Chamartín and take an average of 10h 5m. The schedules shown below are for the next available departures.


9h 7m • 2 changes


8h 36m • 2 changes


8h 38m • 2 changes
Arrives next day


15h 4m • 2 changes


9h 7m • 2 changes


8h 36m • 2 changes


8h 38m • 2 changes
Arrives next day


15h 4m • 2 changes


9h 7m • 2 changes


8h 36m • 2 changes


8h 38m • 2 changes
Arrives next day


15h 19m • 2 changes
Want to know about travelling from Santander to San Isidro? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santander to San Isidro. However, there are services departing from Santander station and arriving at San Isidro station via Madrid Chamartín. The journey, including transfers, takes approximately 10h 5m.
Santander to San Isidro train services, operated by Renfe Viajeros, depart from Santander station.
Santander to San Isidro train services, operated by Renfe Viajeros, arrive at Alacant/Alicante Terminal station.
Book your Santander to San Isidro train tickets online with Renfe Viajeros, Renfe AVE and Renfe Cercanias.
The distance between Santander and San Isidro is 639.3 km. The road distance is 978 km.
You can take a train from Santander to San Isidro-Albatera-Catral via Madrid Chamartín, Alacant/Alicante Terminal, and Alicante/Alacant-Terminal in around 8h 44m.