The train between Santee and La Mesa takes 30 min. The train runs at least 3 times per hour from Santee to La Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 20 minutes between Santee and La Mesa. The earliest departure is at 8:12 AM in the morning, and the last departure from Santee is at 8:57 PM which arrives into La Mesa at 9:27 PM. All services require a transfer, and take on average 30 min. The schedules shown below are for the next available departures.

30 min • 1 change

30 min • 1 change

30 min • 1 change

30 min • 1 change
Want to know about travelling from Santee to La Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santee to La Mesa. However, there are services departing from Santee station and arriving at La Mesa station via El Cajon Station station. The journey, including transfers, takes approximately 30 min.
Santee to La Mesa train services, operated by San Diego Metro Transit, depart from Santee Town Center Station.
Santee to La Mesa train services, operated by San Diego Metro Transit, arrive at La Mesa Blvd Station.
The distance between Santee and La Mesa is 9.1 km. The road distance is 13 km.
You can take a vehicle from Santee Town Center Station to La Mesa Blvd Station via El Cajon Station in around 31 min.