The average train between Santhià and Florence takes 3h 50m and the fastest train takes 3h 26m. There is a train service every few hours from Santhià to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Santhià and Florence. The earliest departure is at 5:38 AM in the morning, and the last departure from Santhià is at 10:38 PM which arrives into Florence at 7:04 AM. All services require a transfer, and take on average 3h 50m. The schedules shown below are for the next available departures.

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change

3h 26m • 1 change
Want to know about travelling from Santhià to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santhià to Florence. However, there are services departing from Santhià station and arriving at Florence station via Milano Centrale. The journey, including transfers, takes approximately 3h 50m.
Santhià to Florence train services, operated by Trenitalia, depart from Santhia station.
Santhià to Florence train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Santhià to Florence train tickets online with Trenitalia and Trenitalia Frecce.
The distance between Santhià and Florence is 300.6 km. The road distance is 395 km.
You can take a train from Santhia to Firenze S.M.N. via Milano Centrale in around 3h 20m.