The average train between Santhià and Rome takes 5h 15m and the fastest train takes 4h 41m. There is a train service every few hours from Santhià to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Santhià and Rome. The earliest departure is at 5:38 AM in the morning, and the last departure from Santhià is at 10:38 PM which arrives into Rome at 9:24 AM. All services require a transfer, and take on average 5h 15m. The schedules shown below are for the next available departures.

4h 52m • 1 change

4h 47m • 1 change

4h 41m • 1 change

4h 43m • 1 change

4h 47m • 1 change

4h 47m • 1 change

4h 41m • 1 change

5h 37m • 1 change

4h 47m • 1 change

4h 47m • 1 change

4h 41m • 1 change

5h 37m • 1 change

4h 47m • 1 change

4h 47m • 1 change

4h 41m • 1 change

5h 37m • 1 change

4h 47m • 1 change

4h 47m • 1 change

4h 41m • 1 change

5h 37m • 1 change
Want to know about travelling from Santhià to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santhià to Rome. However, there are services departing from Santhià station and arriving at Rome station via Rho-Fiera Milano. The journey, including transfers, takes approximately 5h 15m.
Santhià to Rome train services, operated by Trenitalia, depart from Santhia station.
Santhià to Rome train services, operated by Trenitalia, arrive at Roma Termini station.
Book your Santhià to Rome train tickets online with Trenitalia and ItaloTreno.
The distance between Santhià and Rome is 519.2 km. The road distance is 651 km.
You can take a train from Santhia to Roma Termini via Milano Rogoredo in around 4h 7m.