The average train between Santo Spirito and Lecce takes 2h 23m and the fastest train takes 1h 49m. There is a train service every few hours from Santo Spirito to Lecce. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Santo Spirito and Lecce. The earliest departure is at 6:11 AM in the morning, and the last departure from Santo Spirito is at 11:23 PM which arrives into Lecce at 7:12 AM. All services require a transfer, and take on average 2h 23m. The schedules shown below are for the next available departures.

2h 11m • 1 change

2h 11m • 1 change

2h 8m • 1 change

1h 57m • 1 change

2h 2m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 38m • 1 change

2h 1m • 1 change

2h 35m • 1 change

2h 27m • 1 change
Want to know about travelling from Santo Spirito to Lecce? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santo Spirito to Lecce. However, there are services departing from Santo Spirito station and arriving at Lecce station via Lecce. The journey, including transfers, takes approximately 2h 23m.
Santo Spirito to Lecce train services, operated by Trenitalia, depart from Bari Centrale station.
Santo Spirito to Lecce train services, operated by Trenitalia, arrive at Lecce station.
Book your Santo Spirito to Lecce train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Santo Spirito and Lecce is 150 km. The road distance is 161 km.
Trenitalia Frecce operates a train from Bari Centrale to Lecce hourly. Tickets cost €22–45 and the journey takes 1h 21m. Two other operators also service this route.