The average train between Seregno and Florence takes 3h 28m and the fastest train takes 3h 5m. There is a train service every few hours from Seregno to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Seregno and Florence. The earliest departure is at 4:59 AM at night, and the last departure from Seregno is at 9:59 PM which arrives into Florence at 7:04 AM. All services require a transfer, and take on average 3h 28m. The schedules shown below are for the next available departures.

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Want to know about travelling from Seregno to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Seregno to Florence. However, there are services departing from Seregno station and arriving at Florence station via Firenze S.M.N.. The journey, including transfers, takes approximately 3h 28m.
Seregno to Florence train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Milano Centrale station.
Seregno to Florence train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Firenze S.M.N. station.
Book your Seregno to Florence train tickets online with Swiss Federal Railways (SBB CFF FFS) and Trenitalia Frecce.
The distance between Seregno and Florence is 263.2 km. The road distance is 326 km.
Trenitalia Frecce operates a train from Milano Centrale to Firenze S.M.N. hourly. Tickets cost €45–90 and the journey takes 1h 54m. Two other operators also service this route.