The average train between Sesto Calende and Lausanne takes 6h 2m and the fastest train takes 4h 15m. The train service runs several times per day from Sesto Calende to Lausanne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Sesto Calende and Lausanne. The earliest departure is at 7:05 AM in the morning, and the last departure from Sesto Calende is at 8:33 PM which arrives into Lausanne at 11:48 AM. All services require a transfer, and take on average 6h 2m. The schedules shown below are for the next available departures.

4h 43m • 1 change
8h 15m • 1 change
4h 15m • 1 change
4h 40m • 1 changeWant to know about travelling from Sesto Calende to Lausanne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sesto Calende to Lausanne. However, there are services departing from Sesto Calende station and arriving at Lausanne station via Domodossola. The journey, including transfers, takes approximately 6h 2m.
Sesto Calende to Lausanne train services, operated by Trenitalia, depart from Sesto Calende station.
Sesto Calende to Lausanne train services, operated by Trenitalia, arrive at Lausanne station.
Book your Sesto Calende to Lausanne train tickets online with Trenitalia and Swiss Federal Railways (SBB CFF FFS).
The distance between Sesto Calende and Lausanne is 177.6 km. The road distance is 247 km.
You can take a train from Sesto Calende to Lausanne via Domodossola in around 4h 21m.