Sesto Calende to Siena Trains

Sesto Calende to Siena trains

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Trip Overview

The average train between Sesto Calende and Siena takes 6h 27m and the fastest train takes 5h 14m. The train service runs several times per day from Sesto Calende to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 27m
Duration: 453 km
Distance: €68
Average price: Every 4 hours
Frequency

Train via Bologna

best

Take the train from Sesto Calende to Rho-Fiera Milanotrain Re
Take the train from Milano Rogoredo to Bologna centraletrain
Take the train from Bologna Centrale to Firenze S.M.N.train Fr
Take the train from Firenze S.M.N. to Sienatrain Re

4h 56m

€52–101

Sesto Calende to Siena train times

Trains run every 4 hours between Sesto Calende and Siena. The earliest departure is at 7:19 AM in the morning, and the last departure from Sesto Calende is at 9:25 PM which arrives into Siena at 9:38 AM. All services require a transfer at Milano Rogoredo and take an average of 6h 27m. The schedules shown below are for the next available departures.

Departing Sunday, October 25, 2026

7:19 AM → 12:38 PM
5h 19m • 3 changes
1:25 PM → 6:40 PM
5h 15m • 3 changes
3:25 PM → 8:40 PM
5h 15m • 3 changes
5:25 PM → 7:55 AM
Arrives next day
14h 30m • 3 changes
Show more

Departing Monday, October 26, 2026

7:19 AM → 12:38 PM
5h 19m • 3 changes
8:26 AM → 1:40 PM
5h 14m • 3 changes
11:25 AM → 4:40 PM
5h 15m • 3 changes
1:25 PM → 6:40 PM
5h 15m • 3 changes
Show more

Departing Tuesday, October 27, 2026

7:19 AM → 12:38 PM
5h 19m • 3 changes
8:26 AM → 1:40 PM
5h 14m • 3 changes
11:25 AM → 4:40 PM
5h 15m • 3 changes
1:25 PM → 6:40 PM
5h 15m • 3 changes
Show more

Departing Wednesday, October 28, 2026

7:19 AM → 12:38 PM
5h 19m • 3 changes
8:26 AM → 1:40 PM
5h 14m • 3 changes
11:25 AM → 4:40 PM
5h 15m • 3 changes
1:25 PM → 6:40 PM
5h 15m • 3 changes
Show more

Departing Thursday, October 29, 2026

7:19 AM → 12:38 PM
5h 19m • 3 changes
8:26 AM → 1:40 PM
5h 14m • 3 changes
11:25 AM → 4:40 PM
5h 15m • 3 changes
1:25 PM → 6:40 PM
5h 15m • 3 changes
Show more

Departing Friday, October 30, 2026

7:19 AM → 12:38 PM
5h 19m • 3 changes
8:26 AM → 1:40 PM
5h 14m • 3 changes
11:25 AM → 4:40 PM
5h 15m • 3 changes
1:25 PM → 6:40 PM
5h 15m • 3 changes
Show more

Departing Saturday, October 31, 2026

7:19 AM → 12:38 PM
5h 19m • 3 changes
8:26 AM → 1:40 PM
5h 14m • 3 changes
11:25 AM → 4:40 PM
5h 15m • 3 changes
1:25 PM → 6:40 PM
5h 15m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Sesto Calende to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.