The average train between Sestri Ponente and Milan takes 3h 5m and the fastest train takes 2h 55m. The train service runs several times per day from Sestri Ponente to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Sestri Ponente and Milan. The earliest departure is at 6:07 AM in the morning, and the last departure from Sestri Ponente is at 8:54 PM which arrives into Milan at 11:55 PM. All services require a transfer, and take on average 3h 5m. The schedules shown below are for the next available departures.

3h 3m • 1 change

3h 4m • 1 change

3h 30m • 1 change

2h 55m • 1 change

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2h 55m • 1 change

3h 3m • 1 change

3h 4m • 1 change

3h 30m • 1 change

2h 55m • 1 change

3h 3m • 1 change

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3h 30m • 1 change

2h 55m • 1 change

3h 3m • 1 change

3h 4m • 1 change

3h 38m • 1 change

2h 55m • 1 change
Want to know about travelling from Sestri Ponente to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sestri Ponente to Milan. However, there are services departing from Sestri Ponente station and arriving at Milan station via Milano Centrale. The journey, including transfers, takes approximately 3h 5m.
Sestri Ponente to Milan train services, operated by Trenitalia, depart from Genova P.Za Principe station.
Sestri Ponente to Milan train services, operated by Trenitalia, arrive at Milano Centrale station.
Book your Sestri Ponente to Milan train tickets online with Trenitalia and Trenitalia Intercity.
The distance between Sestri Ponente and Milan is 118.6 km. The road distance is 145 km.
Trenitalia Intercity operates a train from Genova P.Za Principe to Milano Centrale every 30 minutes. Tickets cost €15–35 and the journey takes 1h 36m. Two other operators also service this route.